GEA at 2009 AAPS Annual Meeting and Exposition

GEA Pharma Systems - Innovation never stops

For GEA Pharma Systems, innovation is the key to our success and to continued prosperity for our customers. In fact it's more than that. We know that by continually stretching the boundaries of what is possible in pharmaceutical processing we have the ability to support our Customers in enhancing the opportunities available to millions of people all over the world. This is what drives our business.

Our innovation takes many forms and affects all parts of the process. We innovate to increase production and reduce costs, to improve containment and safeguard the workforce, to achieve better clinical effectiveness and to enhance quality control.

GEA Pharma Systems combines state-of-the-art solutions from leading industry brands such as Buck for contained materials handling based on their proven split-valve technology, GEA Courtoy for tablet compression taking advantage of the MODUL™ technology, GEA Niro for spray drying offering unique solutions for inhalation, taste masking, encapsulation and for direct compression, GEA Lyophil for lyophillization (freeze drying) where our products range from small laboratory machines up to production systems including Automatic Loading and Unloading Systems (ALUS®), GEA Aeromatic-Fielder and GEA Collette for granulation, coating and drying technologies including for ULTIMAPRO™ Single Pot Processor or for coating the fluid bed Precision UltimaPro COATER™ and introducing the NEW continuous CONSIGMA™ granulation and drying system.

• Granulation & Drying
  • High Shear Mixer / Granulator
    • Collette MicroGral™ - batch size 100 to 700 g
    • Collette UltimaGral™ 10 & 25 - batch size 1 to 9 kg
    • Aeromatic-Fielder PMA™ 1, 25 & 65 - batch size 1 to 26 kg
    • NEW PharmaConnect™ - 'plug and play' approach enables a number of diverse process modules from GEA Pharma companies to be docked to ONE control module - batch sizes from 100g to 25 kg and over.
  • Fluid bed Processors
    • the Aeromatic-Fielder GMP Strea™ US Advanced laboratory fluid bed processor for dry mixing, liquid spray addition, granulation and agglomeration, coating and drying - batch size 200 g to 2 kg
    • Aeromatic-Fielder MP-1™ - batch size 200 g to 6 kg
  • Single Pot Processing
    • Collette UltimaPro™ 10 & 25 - batch size 1 to 9 kg
  • Continuous Processing
    • NEW Consigma™ Granulation & Drying
• Mixing & Blending
  • Buck Systems SP15 NIR Laboratory Blender with Process Analytical Technology - 5, 10 and 15L container
• Tablet Compression
  • GEA Courtoy Modul™ P tablet press for small-scale production and galenic development
• Freeze Drying
  • GEA Lyophil Lyovac® - Research and Development Freeze Dryers
• Containment Interfaces
  • Hicoflex® - disposable high containment interface
• Pelletizing
  • NICA™ Pelletizing System
    • Aeromatic-Fielder NICA™ M6 Mixer - 2 to 6 kg/min
    • Aeromatic-Fielder NICA™ E140 Extruder - 0.5 to 2 kg/min
    • Aeromatic-Fielder NICA™ S320 Spheronizer - 0.2 to 1 kg
  • Fluid bed Processors
    • Aeromatic-Fielder MP-1™ - batch size 200 g to 6 kg
• Coating
  • Fluid bed Processors
    • Aeromatic-Fielder MP-Micro™ - batch size 20 to 200 g (smallest batch size on the market!)
    • the Aeromatic-Fielder GMP Strea™ US Advanced laboratory fluid bed processor for dry mixing, liquid spray addition, granulation and agglomeration, coating and drying - batch size 200 g to 6 kg
  • Tablet coater
    • Supercell™ Tablet Coating Technology (SCT) - batch size 30 to 120 g
• Spray Drying
  • GEA Niro SDMicro™- Capacity: The evaporative capacity is 500-1000 g/h and the minimum feed requirement is a 50 ml solution and not less than 0.5 g of solids.
• PAT
  • The goal of the PAT initiative is to ensure that pharmaceutical products are developed and manufactured using processes which are understood and monitored so that the key quality characteristics of the products can be actively controlled. This is a vital technology regardless of scale and GPS has the knowledge, experience and tools to support you.

GEA Liquid Processing

GEA Liquid Processing is more known for their comprehensive systems engineering and project management capabilities for the pharmaceutical, biotech & personal care industries. However, they have in their portfolio a range of unique development systems including:

• High-Pressure Homogenization / Cell Disruption
  • GEA Niro Soavi VHP PANDA homogenizer. The PANDA homogenizer is a tabletop model designed for the laboratory needs of biotechnology, cosmetic and pharmaceutical companies. It is a unique unit, with the ability to process small volumes of liquids and pumpable fluids, homogenizing samples at rates up to approx. 160 ml/min, at pressures that can reach 21,750 psi. The internal design has special features permitting the homogenizer to handle feeds at high viscosity up to 20,000 cP and at temperatures up to 90°C without any feeding pump. Tough construction materials enable testing of abrasive, aggressive, or corrosive fluids. The GEA Niro Soavi VHP PANDA homogenizer has proven especially efficient in many cell rupture (cell disruption) applications including bacteria, yeast, algae and plant cells.
• Fermentation
  • GEA Diessel fermentors and bioreactors for microbial and cell fermentation 100 L - 10,000 L and beyond. GEA Diessel has a solution for all of your bioprocessing / fermentation needs because we understand bioreactors and the processes required to produce pharmaceuticals under strict cGMP guidelines.
• Mixing
  • The Batch Formula™ Mixing Systems is an extremely versatile powder liquid mixing system. The system is available for a range of different batch capacities from 50 l (13 Gal.) to 15,000 l (3,900 Gal.).
• Process Integration and Process Automation
  • we integrate equipment, systems and components into your operating plant and provide complete process automations systems for monitoring and control of all process steps, including information and management systems finalized upon customer detailed requirements. - less applicable in development settings
• Cleaning Technology
  • for cleaning-in-place (CIP) and sterilization-in-place (SIP) we offer optimal systems for every task. We have developed single use, recovery, CIP systems and automatic washing cabin systems for cleaning and drying of mobile bulk containers. The product recovery system has been developed to reduce valuable product losses, by integrating this with the process.

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